亚洲第一极品无码,国产精品自在在线观看,亚洲国内偷拍福利,激情av五月天免费观看,四虎影视 国产精品,无码_国产手机在线a√

Service and cooperation

Antibody Humanization

Murine antibody can cause immunogenicity and reduced efficacy in human body. Antibody humanization can reduce the immunogenicity of murine monoclonal antibody. A common approach for humanization is complementary determining regions (CDR) grafting, in which 6 CDRs from a murine antibody are grafted onto a human antibody framework (FR). Some residues from the murine framework sequences need to be retained to replace the human residues at the corresponding positions (back mutations) in order to restore some of the lost affinity. Full-length IgG display libraries which containing FR/CDR variants are the best format to screen for binding properties in antibody humanization.

Based on extensive experience and full-length IgG pichia display, Genekine provides premium quality service to generate humanized antibody. The humanized antibody has comparable binding affinity with parental antibody, and contains over 90% of human amino acid sequences.

 

1. Antibody sequence and structure analysis;

2. 3-D structural modeling;

3. Construction and display of full-length IgG humanization library;

4. FACS sorting to screen for IgG with high binding affinity and expression level. 


    Contact us

    0571-89059592

    Email:info@genekine.com.cn

    Add:Room 1001, Unit 6, Building 6, No. 1500, Wenyi West Road, Yuhang District, Hangzhou City, Zhejiang Province

Follow us

Hangzhou Jingyinkang Biological Technology Co., Ltd. | 浙ICP備15033920號(hào) | Technical Support:REVAN

Hangzhou Jingyinkang Biological Technology Co., Ltd.

Follow us

Online
Tel

0571-89059592

临西县| 扎兰屯市| 霍城县| 宁津县| 罗山县| 娱乐| 双牌县| 双辽市| 克拉玛依市| 融水| 莎车县| 永年县| 孝义市| 威海市| 聂荣县| 揭阳市|